The Mar Thoma Yuvajana Sakhyam was organized with a view that all the young people in the Church should accept Jesus Christ as their saviour and Lord, and bear witness to His saving power. It was organized in 1933 by a resolution of the Sabha Prathinidhi Mandalam. The first president of the Sakhyam was Rev. V. P. Mammen and the Vice- Presidents were Rev. K. E. Oommen and Rev. C. M. John (later Juhanon Mar Thoma Metropolitan) and the first Secretary was Mr. V. E. Thomas (later Rev. V. E. Thomas, Singapore). Branches of the Sakhyam were set up in the Parishes with a four-fold programme of worship, study, witness and service.

The Mar Thoma Voluntary Evangelists’ Association (MTVEA) serves as an organization in the church that emphasizes on the ministry of the laity in the church. Rt. Rev. Dr. Abraham Mar Thoma founded the organisation in 1924 with the goal that every member of the Mar Thoma church is a missionary. Sadhu Kochukunju Upadesi was the first General Secretary. The parish unit of MTVEA is the Edavaka Mission, which plays an important role in the spiritual regeneration of the parish and executes the church's mission.

The main goal of MTVEA is to testify Jesus Christ in our daily lives and to instil in everyone the awareness that he or she is called to accomplish Jesus Christ's mission, regardless of their profession. MTVEA's primary activities include Intercession, Bible Study, Experience sharing, House visits, Serving the Sick, Witnessing, and Fellowship.

The major programs organized by the MTVEA, Mumbai Diocese includes a three-day conference 'Witness', Lay Leaders Training Programs, Seminars, Mission Field Visits, Lent Meditation program, Supporting Student in Bible school, etc. Jeevamrutham is an upcoming Bible course, initiated by MTVEA , Mumbai Diocese.

The MTVEA - Mumbai Diocese consists of 7 centres namely Mumbai, Navi Mumbai, Kalyan, Pune, Gujarat, and Goa. All of the Edavaka Mission's centres and parishes arrange programmes and actively engage in the Diocesan and Parish events, as well as their mission activities.

• Mumbai Centre: The centre organizes a 6 Months Lay leaders training program conducted by Dharma Jyoti Vidya Peeth Seminary, Faridabad. It also supports Navjeevan, Navodaya, Tribal Students, Bible School students. Organized a mission visit and provided assistance to mission fields. Organized Musical evening Sangeetha Sopanam and Bible Quiz Competition etc.
• Navi Mumbai Centre: Conducting bible study, Monthly fellowship meeting, visiting the sick and elderly.
• Kalyan Centre: Conducting night vigil, Bible study, Seminars etc.
• Pune Centre: The Centre is supporting Chaken and Kalechawadi Mission. The centre also organizes Seminars and Bible studies.
• Gujarat Centre: The centre supports Ahwa, Chinchli, Pipalpada Missions. Other Activities include Bible study, Mission Field Visits, Lent Meditation, etc.
• Goa Centre : Conducted Webinars, seminars and Bible study.

The Mar Thoma Suvishesha Sevika Sangham (Women's Wing), was inaugurated during the Maramon Convention in the year 1919 under the leadership of Abraham Mar Thoma Suffragan Metropolitan who gave the sangham continued support and inspiration. Mrs. Kandamma Varghese as organizing Secretary for over 20 years travelling far and wide, organizing branches in parishes, doing evangelistic work among Christians and non‐Christians. Every woman of the Mar Thoma Church, from the age of 18 years is a member of the Sevika Sangham.

Mar Thoma Suvishesha Sevika Sangham of Mumbai Diocese has many activities among the underprivileged children and women in the society. Around 60 downtrodden tribal children stay in Mitra Niketan Girls Hostel in Pipalpada and the Diocesan Sevika Sangham meet all their financial needs. The organization also focus on empowering these children in all prospects. A new venture was initiated to provide financial aid to cancer patients /terminally ill. In accordance with the centenary program of Suvishesha Sevika Sangham, a poultry farm was built at Navjeevan Centre.

The Mumbai Diocese Sevika Sangham consists of 7 Centers: Mumbai, Navi Mumbai, Kalyan, Pune, Gujarat, Goa, Muscat (Ruwi & Sohar). Mumbai Diocesan Sevika Sangham constantly work to help the women of Mar Thoma Church to witness Christ in their spiritual journey and to participate in the mission activities of the church.

The reformers realized the importance of Bible Study, as essential for spiritual renewal and growth. The opening of the Sunday Schools thus became a natural development in the way of Christian nurture. The formal inauguration of the Sunday School Samajam comprising all the Sunday Schools, which had already been started in the parishes, took place at Maramon Convention in 1905. Mr. V. P. Mammen, (later Vicar General V. P. Mammen Kasseesa) was elected as the General Secretary.

Sunday Schools are arranged in every Parish and in large Parishes there will be two or more Sunday Schools according to the need. Inspectors are allotted to supervise the work of Sunday Schools in given area, and organizers are appointed in each diocese. The Central Office arranges examination every year and competitions are also held at the Diocesan and Central level.

Though Senior Citizens Fellowship was active at Centre level in Mumbai, the need for a Diocesan level fellowship was felt by senior members of the various centres. The same request was then presented to the then Diocesan Episcopa Rt. Rev. Dr. Thomas Mar Theethos who directed a meeting to be held addressing this cause. The meeting was held on 12th March, 2016 at St. Thomas Mar Thoma Church, Santacruz under the leadership of Rt. Rev. Dr. Thomas Mar Theethos which led to the formation of The Mar Thoma Senior Citizens fellowship, Mumbai diocese. Every member of Mar Thoma Church above 60 years is a member of this fellowship. This fellowship facilitates individual’s upliftment both spiritual and mental, enables to use one’s abilities and their years of experience for well-being of the church. The major activities of the Mar Thoma Senior Citizen Fellowship, of the Mumbai Diocese, include One Day Conference, Welfare activities, webinars, etc.